GM2A Antibody - N-terminal region : HRP (ARP46007_P050-HRP)
Selected Variant
ARP46007_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
GM2 ganglioside activator
Gene Aliases
SAP-3, GM2-AP
Gene ID
2760
Swiss Prot
P17900
Accession Number
NP_000396
Host
Rabbit
Reactivity
Human, Guinea Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GM2A
Target
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Partner Proteins
ELAVL1; UBC; HEXA; GPLD1; PLD2
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Guinea Pig: 83%; Human: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
21
Shipping Conditions
Wet Ice
Protein Length
193
NCBI Gene Symbol
GM2A
NCBI GB Accession Number
GM2A
Host or Source
Rabbit
Protein Name
Ganglioside GM2 activator
Nucleotide Accession Number
NM_000405
Peptide Sequence
SWDNCDEGKDPAVIRSLTLEPDPIIVPGNVTLSVMGSTSVPLSSPLKVDL
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