GM2A Antibody - N-terminal region : FITC (ARP46007_P050-FITC)
Product Specifications
Gene Name
GM2 ganglioside activator
Gene Aliases
SAP-3, GM2-AP
Gene ID
2760
Swiss Prot
P17900
Accession Number
NP_000396
Host
Rabbit
Reactivity
Human, Guinea Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GM2A
Target
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Partner Proteins
ELAVL1; UBC; HEXA; GPLD1; PLD2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Guinea Pig: 83%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
21
Shipping Conditions
Wet Ice
Product Datasheet
Anti-GM2A (ARP46007_P050-FITC) antibody
Protein Length
193
NCBI Gene Symbol
GM2A
NCBI GB Accession Number
GM2A
Host or Source
Rabbit
Protein Name
Ganglioside GM2 activator
Nucleotide Accession Number
NM_000405
Peptide Sequence
SWDNCDEGKDPAVIRSLTLEPDPIIVPGNVTLSVMGSTSVPLSSPLKVDL
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