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MRPS6 Antibody - middle region: FITC (ARP45882_P050-FITC)

Product Specifications

Gene Name

Mitochondrial ribosomal protein S6

Gene Aliases

S6mt, RPMS6, MRP-S6, C21orf101

Gene ID

64968

Swiss Prot

P82932

Accession Number

NP_115865

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MRPS6

Target

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q.

Partner Proteins

MKRN3; SRPK2; ICT1; RNF181; STAT5A; SREBF2; APP; SRRM2; LRIF1; KIAA1377

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 92%; Dog: 92%; Guinea Pig: 77%; Horse: 85%; Human: 100%; Mouse: 86%; Pig: 92%; Rabbit: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

14kDa

Shipping Conditions

Wet Ice

Protein Length

125

NCBI Gene Symbol

MRPS6

Protein Name

28S ribosomal protein S6, mitochondrial

Nucleotide Accession Number

NM_032476

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