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POFUT2 Antibody - N-terminal region : HRP (ARP45855_P050-HRP)

Selected Variant

ARP45855_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Protein O-fucosyltransferase 2

Gene Aliases

FUT13, C21orf80

Gene ID

23275

Swiss Prot

Q9Y2G5

Accession Number

NP_598368

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human POFUT2

Target

POFUT2 catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats. Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530) -like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]) .[supplied by OMIM].

Partner Proteins

USP22

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Luo, Y., (2006) J. Biol. Chem. 281 (14), 9385-9392

Shipping Conditions

Wet Ice

Protein Length

429

NCBI Gene Symbol

POFUT2

NCBI GB Accession Number

POFUT2

Host or Source

Rabbit

Protein Name

GDP-fucose protein O-fucosyltransferase 2

Nucleotide Accession Number

NM_133635

Peptide Sequence

GAASRRRYLLYDVNPPEGFNLRRDVYIRIASLLKTLLKTEEWVLVLPPWG

Price

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