POFUT2 Antibody - N-terminal region : Biotin (ARP45855_P050-Biotin)
Product Specifications
Gene Name
Protein O-fucosyltransferase 2
Gene Aliases
FUT13, C21orf80
Gene ID
23275
Swiss Prot
Q9Y2G5
Accession Number
NP_598368
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human POFUT2
Target
POFUT2 catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats. Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530) -like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]) .[supplied by OMIM].
Partner Proteins
USP22
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
50kDa
References & Citations
Luo, Y., (2006) J. Biol. Chem. 281 (14), 9385-9392
Shipping Conditions
Wet Ice
Product Datasheet
Anti-POFUT2 (ARP45855_P050-Biotin) antibody
Protein Length
429
NCBI Gene Symbol
POFUT2
NCBI GB Accession Number
POFUT2
Host or Source
Rabbit
Protein Name
GDP-fucose protein O-fucosyltransferase 2
Nucleotide Accession Number
NM_133635
Peptide Sequence
GAASRRRYLLYDVNPPEGFNLRRDVYIRIASLLKTLLKTEEWVLVLPPWG
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