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CFAP410 Antibody - N-terminal region : Biotin (ARP45819_P050-Biotin)

Product Specifications

Gene Name

Cilia and flagella associated protein 410

Gene Aliases

RDMS, SMDAX, LRRC76, YF5/A2, C21orf2

Gene ID

755

Swiss Prot

O43822

Accession Number

NP_004919

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human C21orf2

Target

Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.

Partner Proteins

GMCL1; ATOX1; UBC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that C21orf2 is expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

References & Citations

Oh, J.H., (2005) Mamm. Genome 16 (12), 942-954

Shipping Conditions

Wet Ice

Protein Length

256

NCBI Gene Symbol

CFAP410

NCBI GB Accession Number

CFAP410

Host or Source

Rabbit

Protein Name

Protein C21orf2; nuclear encoded mitochondrial protein C21orf2

Nucleotide Accession Number

NM_004928

Peptide Sequence

KLTRKMVLTRAKASELHSVRKLNCWGSRLTDISICQEMPSLEVITLSVNS

Frequently Asked Questions

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