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PSMG1 Antibody - middle region : Biotin (ARP45814_P050-Biotin)

Product Specifications

Gene Name

Proteasome (prosome, macropain) assembly chaperone 1

Gene Aliases

PAC1, DSCR2, PAC-1, C21LRP, LRPC21

Gene ID

8624

Swiss Prot

B5BUN2

Accession Number

NP_982257

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PSMG1

Target

PSMG1 is a chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.

Partner Proteins

SUMO2; SHFM1; UBC; PSMG3; PSMG2; POMP; PSMG1; PSMA7; PSMA6; PSMA5; PSMA2; EHD4; SEC23A; NOL3; LGALS1; CAPZA2; CAPZA1; APEX1; ACO1; BAG3; FN1; BRCA1; UBD; CUL1; PPARD

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PSMG1 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 85%; Guinea Pig: 85%; Horse: 85%; Human: 100%; Mouse: 92%; Rabbit: 77%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

30kDa

References & Citations

Hirano, Y., (2006) Mol. Cell 24 (6), 977-984

Shipping Conditions

Wet Ice

Protein Length

267

NCBI Gene Symbol

PSMG1

NCBI GB Accession Number

PSMG1

Host or Source

Rabbit

Protein Name

Proteasome assembly chaperone 1

Nucleotide Accession Number

NM_203433

Peptide Sequence

TILTCRHVTDYKTSESTGSLPSPFLRALKTQNFKDSACCPLLEQPNIVHD

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