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PSMG1 Antibody - middle region : Biotin (ARP45813_P050-Biotin)

Product Specifications

Gene Name

Proteasome (prosome, macropain) assembly chaperone 1

Gene Aliases

PAC1, DSCR2, PAC-1, C21LRP, LRPC21

Gene ID

8624

Swiss Prot

O95456

Accession Number

NP_003711

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PSMG1

Target

PSMG1 is a chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.

Partner Proteins

SUMO2; SHFM1; UBC; PSMG3; PSMG2; POMP; PSMG1; PSMA7; PSMA6; PSMA5; PSMA2; EHD4; SEC23A; NOL3; LGALS1; CAPZA2; CAPZA1; APEX1; ACO1; BAG3; FN1; BRCA1; UBD; CUL1; PPARD

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

References & Citations

Hirano, Y., (2006) Mol. Cell 24 (6), 977-984

Shipping Conditions

Wet Ice

Protein Length

288

NCBI Gene Symbol

PSMG1

NCBI GB Accession Number

PSMG1

Host or Source

Rabbit

Protein Name

Proteasome assembly chaperone 1

Nucleotide Accession Number

NM_003720

Peptide Sequence

VMKLDLITVEAFKPILSTRSLKGLVKNIPQSTEILKKLMTTNEIQSNIYT

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