USP16 Antibody - N-terminal region : Biotin (ARP45772_T100-Biotin)
Selected Variant
ARP45772_T100-Biotin
Size: 100 µL
Product Specifications
Gene Name
Ubiquitin specific peptidase 16
Gene Aliases
UBPM, UBP-M
Gene ID
10600
Swiss Prot
Q5VKN8
Accession Number
AAR13293
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human USP16
Target
USP16 is a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division.
Partner Proteins
RNF8; HERC2; USP16; HIST1H2AB; XPO1; HIST1H2BB; CDK1; HIST2H2AC; HIST2H2AA3; UBC; IGF2BP3; TXNL1; CSNK1D; HIST4H4; FBXO11; PTOV1; UBD; hist1h3g; CALM1; HIST1H2BL; DBT; EXOSC10
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Pig: 92%; Rabbit: 86%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
44kDa
Shipping Conditions
Wet Ice
Protein Length
408
NCBI Gene Symbol
USP16
NCBI GB Accession Number
USP16
Host or Source
Rabbit
Protein Name
Ubiquitin carboxyl-terminal hydrolase 16
Nucleotide Accession Number
NM_001001992
Peptide Sequence
CKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRS
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