SOD1 Antibody - N-terminal region : Biotin (ARP45752_T100-Biotin)

SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis.The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

SOD1; CRYAB; UBC; SMAD2; HDAC6; GSH1; OPTN; PRDX5; AHCYL1; TIAL1; PRDX2; SPTBN1; SOD2; PPP2CA; PPIA; PLS3; PRDX1; NME2; NME1; Hspa4l; Hspa4; Hspa2; Hspa1b; Hsph1; Dnaja1; Hspa8; Hspa5; Ccs; UBE3A; COMMD1; Stub1; SUMO4; DYNLT1; AMFR; MARCH5; RNF19A; PSMD4

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.