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ECHS1 Antibody - N-terminal region : Biotin (ARP45698_P050-Biotin)

Product Specifications

Gene Name

Enoyl CoA hydratase, short chain, 1, mitochondrial

Gene Aliases

SCEH, ECHS1D

Gene ID

1892

Swiss Prot

P30084

Accession Number

NP_004083

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ECHS1

Target

ECHS1 functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The protein is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

SUMO2; UBC; MDM2; GINS3; SMEK2; CNDP2; DCPS; ABHD14A; YWHAQ; SLC9A3R1; USP14; YWHAZ; VCL; UBE2V1; TGM2; RAP1GDS1; PFAS; HSPA9; GSS; CAPN1; CLDN12; UBA1; PPM1B; SERPINA1; ECHS1; CYP2E1; GRB2; UCHL5; UBA5; DDA1; CBWD2; EPB41

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

References & Citations

Takahashi, M., (2007) Antiviral Res. 75 (2), 152-158

Shipping Conditions

Wet Ice

Protein Length

290

NCBI Gene Symbol

ECHS1

NCBI GB Accession Number

ECHS1

Host or Source

Rabbit

Protein Name

Enoyl-CoA hydratase, mitochondrial

Nucleotide Accession Number

NM_004092

Peptide Sequence

IIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAI

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