CPS1 Antibody - N-terminal region: FITC (ARP45689_T100-FITC)
Product Specifications
Gene Name
Carbamoyl-phosphate synthase 1, mitochondrial
Gene Aliases
PHN, CPSASE1
Gene ID
1373
Swiss Prot
P31327
Accession Number
NP_001866
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CPS1
Target
Carbamoyl phosphate synthetase I is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis.Carbamoyl phosphate synthetase I (EC 6.3.4.16) is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis (CAD; MIM 114010), which has been mapped to 2p21.[supplied by OMIM].
Partner Proteins
AGO2; ASB1; FBXO6; UBC; MRPS26; LRPPRC; TOMM70A; SEC22B; PCBP1; HSPA9; HSPA1A; FH; CPT1A; MYC; ELAVL1; SUMO2; RAD21; Csnk1e; Cdk1; RICTOR; YWHAQ; H2AFX; ARAF; RAF1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 79%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
165kDa
Shipping Conditions
Wet Ice
Protein Length
1500
NCBI Gene Symbol
CPS1
Protein Name
Carbamoyl-phosphate synthase [ammonia], mitochondrial
Nucleotide Accession Number
NM_001875
Curated Selection
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