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CPS1 Antibody - N-terminal region: Biotin (ARP45689_T100-Biotin)

Product Specifications

Gene Name

Carbamoyl-phosphate synthase 1, mitochondrial

Gene Aliases

PHN, CPSASE1

Gene ID

1373

Swiss Prot

P31327

Accession Number

NP_001866

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CPS1

Target

Carbamoyl phosphate synthetase I is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis.Carbamoyl phosphate synthetase I (EC 6.3.4.16) is the rate-limiting enzyme that catalyzes the first committed step of the hepatic urea cycle. The mitochondrial isozyme is designated CPS I and the cytoplasmic enzyme CPS II. CPS II is part of a multifunctional enzyme, called the CAD trifunctional protein of pyrimidine biosynthesis (CAD; MIM 114010), which has been mapped to 2p21.[supplied by OMIM].

Partner Proteins

AGO2; ASB1; FBXO6; UBC; MRPS26; LRPPRC; TOMM70A; SEC22B; PCBP1; HSPA9; HSPA1A; FH; CPT1A; MYC; ELAVL1; SUMO2; RAD21; Csnk1e; Cdk1; RICTOR; YWHAQ; H2AFX; ARAF; RAF1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/mL

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 79%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

165kDa

Shipping Conditions

Wet Ice

Protein Length

1500

NCBI Gene Symbol

CPS1

Protein Name

Carbamoyl-phosphate synthase [ammonia], mitochondrial

Nucleotide Accession Number

NM_001875

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