RORA Antibody - N-terminal region : Biotin (ARP45644_P050-Biotin)
Product Specifications
Gene Name
RAR-related orphan receptor A
Gene Aliases
ROR1, ROR2, ROR3, RZRA, NR1F1, IDDECA, RZR-ALPHA
Gene ID
6095
Swiss Prot
B6ZGS4
Accession Number
NP_599023
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human RORA
Target
The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
Partner Proteins
GFAP; NSD1; NCOA1; PSMC5; SMARCD3; PTBP1; VPRBP; UBC; EZH2; DDB1; LMO3; NR0B1; ZXDC; PNRC2; COPS5; PNRC1; EIF3I; PROX1; LRIF1; RUVBL1; CEBPB; NCOA2; MED1; EP300; RORA; MYOD1; NME2; NME1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Human: 100%; Mouse: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
59kDa
References & Citations
Tordjman, J., (2007) J. Biol. Chem. 282 (32), 23591-23602
Shipping Conditions
Wet Ice
Protein Length
523
NCBI Gene Symbol
RORA
NCBI GB Accession Number
RORA
Host or Source
Rabbit
Protein Name
Retinoid-related orphan receptor alpha EMBL BAH02285.1
Nucleotide Accession Number
NM_134261
Peptide Sequence
ARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHY
More Discoveries
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