Rora Antibody - N-terminal region: FITC (ARP45643_P050-FITC)
Product Specifications
Gene Aliases
Sg, Nr1, ROR1, ROR2, ROR3, Nr1f1, nmf267, tmgc26, staggerer, 9530021D13Rik
Gene ID
19883
Swiss Prot
P51448
Accession Number
NP_038674
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Rora
Target
Rora is an orphan nuclear receptor. It binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. IT is a possible receptor for cholesterol or one of its derivatives.
Partner Proteins
Atxn1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Human: 100%; Mouse: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
59kDa
Shipping Conditions
Wet Ice
Protein Length
523
NCBI Gene Symbol
RORA
Protein Name
Nuclear receptor ROR-alpha
Nucleotide Accession Number
NM_013646
Curated Selection
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