Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

NR1I3 Antibody - N-terminal region : Biotin (ARP45623_T100-Biotin)

Selected Variant

ARP45623_T100-Biotin

Size: 100 µL

Product Specifications

Gene Name

Nuclear receptor subfamily 1, group I, member 3

Gene Aliases

CAR, CAR1, MB67

Gene ID

9970

Swiss Prot

Q5VTW5

Accession Number

NP_005113

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NR1I3

Target

NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.

Partner Proteins

HSP90AA1; RXRA; CHD9; SNX13; SNRPD3; IGH; PSMC5; PSMC4; EIF3I; SRC; MAP4; FTH1; HNF4A; NR0B2; PPARGC1A; MED1; NCOA1; POU1F1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 90%; Dog: 92%; Guinea Pig: 79%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

References & Citations

Ferguson, S.S., (2005) Mol. Pharmacol. 68 (3), 747-757

Shipping Conditions

Wet Ice

Protein Length

348

NCBI Gene Symbol

NR1I3

NCBI GB Accession Number

NR1I3

Host or Source

Rabbit

Protein Name

Nuclear receptor subfamily 1 group I member 3

Nucleotide Accession Number

NM_005122

Peptide Sequence

MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human Kappa Light Chain (L1C1), CF594 conjugate, 0.1mg/mL
Cytochrome C (CTC05), 0.2mg/mL
BNUB0887-500 1x 500 µL

Cytochrome C (CTC05), 0.2mg/mL

Sign In for Pricing
View Details
Human CD47 ELISA Kit PicoKine®
EK1421 96 Well With Removable Strips

Human CD47 ELISA Kit PicoKine®

Sign In for Pricing
View Details