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SSR1 Antibody - N-terminal region : FITC (ARP45426_P050-FITC)

Selected Variant

ARP45426_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Signal sequence receptor, alpha

Gene Aliases

TRAPA

Gene ID

6745

Swiss Prot

P43307

Accession Number

NP_003135

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SSR1

Target

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein.The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.

Partner Proteins

HUWE1; ILK; EDEM1; SERPINF2; SERPINA1; ODC1; MYC; HSPA5; MDC1; SFXN1; HM13; ACAD9; FKBP8; CCT5; CCT2; CCT4; TCP1; SRSF1; PSAP; HNRNPM; ILF3; FLOT2; ABCC2; ATP6V1C1; FBXO6; CAND1; CUL3; ELAVL1; HDGF; UBC; SUMO2; HSPA13; UTP14A; NUP54; DKC1; PTN; EEF1A1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

SSR1 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

References & Citations

Otsuki, T., (2005) DNA Res. 12 (2), 117-126

Shipping Conditions

Wet Ice

Protein Length

286

NCBI Gene Symbol

SSR1

NCBI GB Accession Number

SSR1

Host or Source

Rabbit

Protein Name

Translocon-associated protein subunit alpha

Nucleotide Accession Number

NM_003144

Peptide Sequence

DDEAEVEEDEPTDLVEDKEEEDVSGEPEASPSADTTILFVKGEDFPANNI

Subunit

Alpha

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