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SOAT1 Antibody - middle region: Biotin (ARP45419_P050-Biotin)

Product Specifications

Gene Name

Sterol O-acyltransferase 1

Gene Aliases

ACAT, SOAT, STAT, ACACT, ACAT1, ACAT-1

Gene ID

6646

Swiss Prot

P35610

Accession Number

NP_003092

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SOAT1

Target

Acyl-coenzyme A:cholesterol acyltransferase (ACACT; EC 2.3.1.26) is an intracellular protein located in the endoplasmic reticulum that forms cholesterol esters from cholesterol. Accumulation of cholesterol esters as cytoplasmic lipid droplets within macrophages and smooth muscle cells is a characteristic feature of the early stages of atherosclerotic plaques (Cadigan et al., 1988 [PubMed 3335499]) .

Partner Proteins

UBC; ILF2; SLC25A10; TERF1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

65kDa

Shipping Conditions

Wet Ice

Protein Length

550

NCBI Gene Symbol

SOAT1

Protein Name

Sterol O-acyltransferase 1

Nucleotide Accession Number

NM_003101

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