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SMPD2 Antibody - N-terminal region : FITC (ARP45417_T100-FITC)

Selected Variant

ARP45417_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)

Gene Aliases

ISC1, NSMASE, NSMASE1

Gene ID

6610

Swiss Prot

O60906

Accession Number

NP_003071

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SMPD2

Target

SMPD2 converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) . The physiological substrate seems to be Lyso-PAF.

Partner Proteins

UBC; PIK3CG

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 77%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

References & Citations

Kimura, K., (2006) Genome Res. 16 (1), 55-65

Shipping Conditions

Wet Ice

Protein Length

423

NCBI Gene Symbol

SMPD2

NCBI GB Accession Number

SMPD2

Host or Source

Rabbit

Protein Name

Sphingomyelin phosphodiesterase 2

Nucleotide Accession Number

NM_003080

Peptide Sequence

RQKLSPTYPAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHH

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