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RPN2 Antibody - N-terminal region : HRP (ARP45400_P050-HRP)

Selected Variant

ARP45400_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Ribophorin II

Gene Aliases

SWP1, RPNII, RIBIIR, RPN-II

Gene ID

6185

Swiss Prot

P04844

Accession Number

NP_002942

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RPN2

Target

RPN2 is a type I integral membrane protein found only in the rough endoplasmic reticulum. The protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains.This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1.

Partner Proteins

UBC; FUS; FAF1; VAPB; EED; ADRB2; CLN3; MMS19; RCHY1; UBL4A; ESR1; RHOA; RPN1; ILF3; PDIA3; CANX; ATP5A1; STT3B; TM9SF2; FBXO6; CUL3; FBXO25; SIRT7; TCF3; AUP1; ARRB2; NDRG1; SUMO2; FBN3; RBBP4; NGFR; HDAC5; MYC; RNF185; H2AFX; BRE; ADRM1; EZH2; GSTK1; TM

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

RPN2 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

69kDa

References & Citations

Shibatani, T., (2005) Biochemistry 44 (16), 5982-5992

Shipping Conditions

Wet Ice

Protein Length

631

NCBI Gene Symbol

RPN2

NCBI GB Accession Number

RPN2

Host or Source

Rabbit

Protein Name

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

Nucleotide Accession Number

NM_002951

Peptide Sequence

ASQEALSALTARLSKEETVLATVQALQTASHLSQQADLRSIVEEIEDLVA

Subunit

2

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