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RPN2 Antibody - N-terminal region : Biotin (ARP45400_P050-Biotin)

Product Specifications

Gene Name

Ribophorin II

Gene Aliases

SWP1, RPNII, RIBIIR, RPN-II

Gene ID

6185

Swiss Prot

P04844

Accession Number

NP_002942

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RPN2

Target

RPN2 is a type I integral membrane protein found only in the rough endoplasmic reticulum. The protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains.This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1.

Partner Proteins

UBC; FUS; FAF1; VAPB; EED; ADRB2; CLN3; MMS19; RCHY1; UBL4A; ESR1; RHOA; RPN1; ILF3; PDIA3; CANX; ATP5A1; STT3B; TM9SF2; FBXO6; CUL3; FBXO25; SIRT7; TCF3; AUP1; ARRB2; NDRG1; SUMO2; FBN3; RBBP4; NGFR; HDAC5; MYC; RNF185; H2AFX; BRE; ADRM1; EZH2; GSTK1; TM

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

RPN2 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

69kDa

References & Citations

Shibatani, T., (2005) Biochemistry 44 (16), 5982-5992

Shipping Conditions

Wet Ice

Protein Length

631

NCBI Gene Symbol

RPN2

NCBI GB Accession Number

RPN2

Host or Source

Rabbit

Protein Name

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

Nucleotide Accession Number

NM_002951

Peptide Sequence

ASQEALSALTARLSKEETVLATVQALQTASHLSQQADLRSIVEEIEDLVA

Subunit

2

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