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PTPRN Antibody - middle region : Biotin (ARP45381_P050-Biotin)

Selected Variant

ARP45381_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Protein tyrosine phosphatase, receptor type, N

Gene Aliases

IA2, IA-2, ICA512, R-PTP-N, IA-2/PTP

Gene ID

5798

Swiss Prot

Q16849

Accession Number

EAW70725

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PTPRN

Target

PTPRN is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.

Partner Proteins

PLP1; MAL; CLN8; UBQLN4; SNX19; SPTBN4; PTPRT; MADD; PTPRS; SNTB2; NOS1; PPIA; CAPN2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 85%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 86%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

96kDa

Shipping Conditions

Wet Ice

Protein Length

889

NCBI Gene Symbol

PTPRN

NCBI GB Accession Number

PTPRN

Host or Source

Rabbit

Protein Name

Protein tyrosine phosphatase, receptor type, N EMBL AAP35621.1

Nucleotide Accession Number

NM_001199763

Peptide Sequence

EVQQVPSPVSSEPPKAARPPVTPVLLEKKSPLGQSQPTVAGQPSARPAAE

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