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PI3 Antibody - middle region : Biotin (ARP45341_P050-Biotin)

Product Specifications

Gene Name

Peptidase inhibitor 3, skin-derived

Gene Aliases

ESI, WAP3, SKALP, WFDC14, cementoin

Gene ID

5266

Swiss Prot

P19957

Accession Number

NP_002629

Host

Rabbit

Reactivity

Human, Cow, Pig, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PI3

Target

PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

EVPL; CELA1; LOR; KRT1; CSTA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 85%; Human: 100%; Pig: 77%; Sheep: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

6kDa

References & Citations

Wang, Z., (2008) Am. J. Respir. Cell Mol. Biol. 38 (6), 724-732

Shipping Conditions

Wet Ice

Protein Length

117

NCBI Gene Symbol

PI3

NCBI GB Accession Number

PI3

Host or Source

Rabbit

Protein Name

Elafin

Nucleotide Accession Number

NM_002638

Peptide Sequence

KGRVPFNGQDPVKGQVSVKGQDKVKAQEPVKGPVSTKPGSCPIILIRCAM

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