PI3 Antibody - middle region : Biotin (ARP45341_P050-Biotin)
Product Specifications
Gene Name
Peptidase inhibitor 3, skin-derived
Gene Aliases
ESI, WAP3, SKALP, WFDC14, cementoin
Gene ID
5266
Swiss Prot
P19957
Accession Number
NP_002629
Host
Rabbit
Reactivity
Human, Cow, Pig, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PI3
Target
PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
EVPL; CELA1; LOR; KRT1; CSTA
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 85%; Human: 100%; Pig: 77%; Sheep: 77%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
6kDa
References & Citations
Wang, Z., (2008) Am. J. Respir. Cell Mol. Biol. 38 (6), 724-732
Shipping Conditions
Wet Ice
Protein Length
117
NCBI Gene Symbol
PI3
NCBI GB Accession Number
PI3
Host or Source
Rabbit
Protein Name
Elafin
Nucleotide Accession Number
NM_002638
Peptide Sequence
KGRVPFNGQDPVKGQVSVKGQDKVKAQEPVKGPVSTKPGSCPIILIRCAM
Curated Selection
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