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PCDH8 Antibody - middle region : FITC (ARP45339_P050-FITC)

Product Specifications

Gene Name

Protocadherin 8

Gene Aliases

PAPC, ARCADLIN

Gene ID

5100

Swiss Prot

O95206

Accession Number

NP_116567

Host

Rabbit

Reactivity

Human, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PCDH8

Target

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. PCDH8 is an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.

Partner Proteins

UBQLN4; BTRC; PCDH8

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 92%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Rabbit: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

101kDa

References & Citations

Lim, J., (2006) Cell 125 (4), 801-814

Shipping Conditions

Wet Ice

Protein Length

973

NCBI Gene Symbol

PCDH8

NCBI GB Accession Number

PCDH8

Host or Source

Rabbit

Protein Name

Protocadherin-8

Nucleotide Accession Number

NM_032949

Peptide Sequence

RVFRALLVISDGGRPPLTTTATVSFVVTAGGGRGPAAPASAGSPERSRPP

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