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ATP6AP1 Antibody - middle region : HRP (ARP45065_P050-HRP)

Product Specifications

Gene Name

ATPase, H+ transporting, lysosomal accessory protein 1

Gene Aliases

16A, CF2, Ac45, XAP3, XAP-3, ATP6S1, VATPS1, ATP6IP1

Gene ID

537

Swiss Prot

Q15904

Accession Number

NP_001174

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ATP6AP1

Target

This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules.

Partner Proteins

K3; NR1I2; UBC; nef; HNRNPAB; ATP6V1C1; FBXO6; SYVN1; HBA2; ANG; HBA1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52

Shipping Conditions

Wet Ice

Protein Length

470

NCBI Gene Symbol

ATP6AP1

NCBI GB Accession Number

ATP6AP1

Host or Source

Rabbit

Protein Name

V-type proton ATPase subunit S1

Nucleotide Accession Number

NM_001183

Peptide Sequence

SPVIHPPVSYNDTAPRILFWAQNFSVAYKDQWEDLTPLTFGVQELNLTGS

Subunit

S1

Frequently Asked Questions

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