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ENPP2 Antibody : Biotin (ARP44908_P050-Biotin)

Product Specifications

Gene Name

Ectonucleotide pyrophosphatase/phosphodiesterase 2

Gene Aliases

ATX, NPP2, ATX-X, PDNP2, LysoPLD, AUTOTAXIN, PD-IALPHA

Gene ID

5168

Swiss Prot

Q13822

Accession Number

NP_001035181

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence IPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPL

Target

The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Partner Proteins

ITGB4; LPAR1; Dlg4; UBD

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

99 kDa

Shipping Conditions

Wet Ice

Protein Length

863

NCBI Gene Symbol

ENPP2

NCBI GB Accession Number

ENPP2

Host or Source

Rabbit

Protein Name

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

Nucleotide Accession Number

NM_001040092

Peptide Sequence

IPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPL

Frequently Asked Questions

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