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SIL1 Antibody - N-terminal region : Biotin (ARP44848_P050-Biotin)

Product Specifications

Gene Name

SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)

Gene Aliases

BAP, MSS, ULG5

Gene ID

64374

Swiss Prot

Q9H173

Accession Number

NP_071909

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SIL1

Target

SIL1 is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in its gene have been associated with Marinesco-Sjogren syndrome.This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.

Partner Proteins

UBQLN1; FBXO6; UBC; SMAD9; CCND3; HSPA5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

49kDa

References & Citations

Anttonen, A.K., (2005) Nat. Genet. 37 (12), 1309-1311

Shipping Conditions

Wet Ice

Protein Length

461

NCBI Gene Symbol

SIL1

NCBI GB Accession Number

SIL1

Host or Source

Rabbit

Protein Name

Nucleotide exchange factor SIL1

Nucleotide Accession Number

NM_022464

Peptide Sequence

KETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAK

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