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NRCAM Antibody - N-terminal region : Biotin (ARP44832_P050-Biotin)

Selected Variant

ARP44832_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Neuronal cell adhesion molecule

Gene Aliases

KIAA0343, MGC138845, MGC138846

Gene ID

4897

Swiss Prot

Q4KMQ7

Accession Number

AAH98401

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NRCAM

Target

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. NRCAM is a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM may also play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of its gene have been associated with autism and addiction vulnerability.

Partner Proteins

LNX1; MAGI3; HSPA12A; MACF1; UBC; NFASC; NRCAM; CNTN2; PTPRB; ANK2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

84kDa

Shipping Conditions

Wet Ice

Protein Length

771

NCBI Gene Symbol

NRCAM

NCBI GB Accession Number

NRCAM

Host or Source

Rabbit

Protein Name

NRCAM protein EMBL AAH98401.1

Nucleotide Accession Number

NM_001037132

Peptide Sequence

PLILFLCQMISALEVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGK

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