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LRP8 Antibody - middle region : FITC (ARP44723_P050-FITC)

Product Specifications

Gene Name

Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

Gene Aliases

MCI1, LRP-8, APOER2, HSZ75190

Gene ID

7804

Swiss Prot

B1AMT8

Accession Number

NP_059992

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human LRP8

Target

LRP8 is an apolipoprotein E receptor, a member of the low density lipoprotein receptor (LDLR) family. Apolipoprotein E is a small lipophilic plasma protein and a component of lipoproteins such as chylomicron remnants, very low density lipoprotein (VLDL), and high density lipoprotein (HDL) . The apolipoprotein E receptor is involved in cellular recognition and internalization of these lipoproteins.This gene encodes an apolipoprotein E receptor, a member of the low density lipoprotein receptor (LDLR) family. Apolipoprotein E is a small lipophilic plasma protein and a component of lipoproteins such as chylomicron remnants, very low density lipoprotein (VLDL), and high density lipoprotein (HDL) . The apolipoprotein E receptor is involved in cellular recognition and internalization of these lipoproteins. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.

Partner Proteins

UBC; MYLIP; RELN; APOE; GRIN1; SNX17; DAB1; DLG4; CLU; APOH; LRPAP1; SYNJ2BP; MAPK8IP2; GIPC1; ANAPC10; NOS1AP; MAPK8IP1; ITGB1BP1; SCN3A; APBA2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

References & Citations

Hoe, H.S., (2008) J. Biol. Chem. 283 (10), 6288-6299

Shipping Conditions

Wet Ice

Protein Length

700

NCBI Gene Symbol

LRP8

NCBI GB Accession Number

LRP8

Host or Source

Rabbit

Protein Name

Low-density lipoprotein receptor-related protein 8

Nucleotide Accession Number

NM_017522

Peptide Sequence

ATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGV

Frequently Asked Questions

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