ATP synthase inhibitor 1

ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1].

Product Specifications

CAS Number

[1023043-30-2]

UNSPSC

12352005

Target

ATP Synthase

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/atp-synthase-inhibitor-1.html

Purity

99.56

Solubility

DMSO : 5 mg/mL (ultrasonic)

Smiles

O=C1NCN(C2=CC=CC=C2)C31CCN(S(=O)(C4=CC=C(Cl)S4)=O)CC3

Molecular Formula

C17H18ClN3O3S2

Molecular Weight

411.93

References & Citations

[1]Morciano G, et al. Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction. J Med Chem. 2018 Aug 23;61 (16) :7131-7143.