ATP synthase inhibitor 1
ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1].
Product Specifications
CAS Number
[1023043-30-2]
UNSPSC
12352005
Target
ATP Synthase
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/atp-synthase-inhibitor-1.html
Purity
99.56
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C1NCN(C2=CC=CC=C2)C31CCN(S(=O)(C4=CC=C(Cl)S4)=O)CC3
Molecular Formula
C17H18ClN3O3S2
Molecular Weight
411.93
References & Citations
[1]Morciano G, et al. Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction. J Med Chem. 2018 Aug 23;61 (16) :7131-7143.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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