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WDR33 Antibody - middle region : Biotin (ARP44527_P050-Biotin)

Product Specifications

Gene Name

WD repeat domain 33

Gene Aliases

NET14, WDC146

Gene ID

55339

Swiss Prot

Q6NUQ0

Accession Number

NP_001006624

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human WDR33

Target

WDR33 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Partner Proteins

SUMO1; WWOX; RPA3; RPA2; RPA1; BMI1; CLK2; CDK6; DYRK4; HDAC11; UBC; CDK4; MDC1; BARD1; ZNF622; FIP1L1; CPSF2; CPSF3; CPSF1; MED17; ISG15; HNRNPA1; ELAVL1; SMARCAD1; RBM48; ZBTB16; EEF1G; ZHX1; KAT7; UTP14A; GIT1; SH3GL3; PRMT1; TP53; TGFBR1; PFN2; RNPS1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

WDR33 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

30kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

257

NCBI Gene Symbol

WDR33

NCBI GB Accession Number

WDR33

Host or Source

Rabbit

Protein Name

Pre-mRNA 3' end processing protein WDR33

Nucleotide Accession Number

NM_001006623

Peptide Sequence

TKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETIL

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