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DPP10 Antibody - middle region : FITC (ARP44474_P050-FITC)

Product Specifications

Gene Name

Dipeptidyl-peptidase 10 (non-functional)

Gene Aliases

DPL2, DPPY, DPRP3, DPRP-3

Gene ID

57628

Swiss Prot

Q0GLB7

Accession Number

NP_001004360

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human DPP10

Target

DPP10 is a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma.This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

BAG3; KCND3; KCND2; DPP10

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

90kDa

References & Citations

Hersh, C.P., (2007) Am. J. Respir. Crit. Care Med. 176 (9), 849-857

Shipping Conditions

Wet Ice

Protein Length

789

NCBI Gene Symbol

DPP10

NCBI GB Accession Number

DPP10

Host or Source

Rabbit

Protein Name

DPPY splice variant d EMBL ABI16087.1

Nucleotide Accession Number

NM_001004360

Peptide Sequence

VNYTMQVYPDEGHNVSEKSKYHLYSTILKFFSDCLKEEISVLPQEPEEDE

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