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TRPM2 Antibody - N-terminal region : HRP (ARP44380_P050-HRP)

Selected Variant

ARP44380_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Transient receptor potential cation channel, subfamily M, member 2

Gene Aliases

KNP3, EREG1, TRPC7, LTRPC2, NUDT9H, LTrpC-2, NUDT9L1

Gene ID

7226

Swiss Prot

O94759

Accession Number

NP_003298

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TRPM2

Target

TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; TRPC6; ITPR3

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 88%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

171kDa

References & Citations

Hecquet, C.M., (2008) Circ. Res. 102 (3), 347-355

Shipping Conditions

Wet Ice

Protein Length

1503

NCBI Gene Symbol

TRPM2

NCBI GB Accession Number

TRPM2

Host or Source

Rabbit

Protein Name

Transient receptor potential cation channel subfamily M member 2

Nucleotide Accession Number

NM_003307

Peptide Sequence

VAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFMDEWQWK

Price

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