TNF Antibody - C-terminal region : Biotin (ARP44316_P050-Biotin)

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

LAMP2; CASP8; RNF8; FADD; RIPK1; TRADD; UBE2N; UBC; TRAF2; TNFRSF1A; RAB5A; HNRNPA1; CHUK; PSMD9; OTULIN; RNF31; TNFRSF1B; NFKBIA; LYN; FYN; YWHAQ; ZFP36; OPTN; RBCK1; IKBKG; TNFAIP3; HNRNPD; ELAVL1; SHARPIN; AGO2; HSPB2; HSPB1; MAP3K7; IKBKB; TAB2; TAB1

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.