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HFE Antibody - N-terminal region : HRP (ARP44283_P050-HRP)

Selected Variant

ARP44283_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Hemochromatosis

Gene Aliases

HH, HFE1, HLA-H, MVCD7, TFQTL2

Gene ID

3077

Swiss Prot

Q30201

Accession Number

NP_000401

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HFE

Target

HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M) . It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.

Partner Proteins

B2M; SYVN1; UBC; TFR2; TFRC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that HFE is expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40

Shipping Conditions

Wet Ice

Protein Length

348

NCBI Gene Symbol

HFE

NCBI GB Accession Number

HFE

Host or Source

Rabbit

Protein Name

Hereditary hemochromatosis protein

Nucleotide Accession Number

NM_000410

Peptide Sequence

MGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMW

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