HFE Antibody - N-terminal region : Biotin (ARP44283_P050-Biotin)

Product Specifications

Gene Name

Hemochromatosis

Gene Aliases

HH, HFE1, HLA-H, MVCD7, TFQTL2

Gene ID

3077

Swiss Prot

Q30201

Accession Number

NP_000401

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HFE

Target

HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M) . It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.

Partner Proteins

B2M; SYVN1; UBC; TFR2; TFRC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that HFE is expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.