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EXT2 Antibody - N-terminal region : HRP (ARP44277_P050-HRP)

Product Specifications

Gene Name

Exostosin 2

Gene Aliases

SOTV, SSMS

Gene ID

2132

Swiss Prot

Q93063

Accession Number

NP_000392

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EXT2

Target

EXT2 is one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis.This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Partner Proteins

UBC; GSKIP; SLC22A2; CDKN1A; ANXA7; TK1; SMN1; PFDN1; GALNT5; TRAP1; EXT2; EXT1; CLEC2L; CRB1; HYOU1; STK16; TCEB1; SNCG; RPS29; HNF4A; FABP4; CNTF

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

EXT2 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 93%; Zebrafish: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

82kDa

References & Citations

Leube, B., (2008) Genet. Test. 12 (1), 129-133

Shipping Conditions

Wet Ice

Protein Length

718

NCBI Gene Symbol

EXT2

NCBI GB Accession Number

EXT2

Host or Source

Rabbit

Protein Name

Exostosin-2

Nucleotide Accession Number

NM_000401

Peptide Sequence

NELLMAISDSDYYTDDINRACLFVPSIDVLNQNTLRIKETAQAMAQLSRW

Frequently Asked Questions

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