MICA Antibody - middle region : FITC (ARP44247_T100-FITC)
Selected Variant
ARP44247_T100-FITC
Size: 100 µL
Product Specifications
Gene Name
MHC class I polypeptide-related sequence A
Gene Aliases
PERB11.1
Gene ID
4276
Accession Number
NP_000238
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human MICA
Target
MICA is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
42kDa
References & Citations
Boissel, N., (2006) J. Immunol. 176 (8), 5108-5116
Shipping Conditions
Wet Ice
Protein Length
383
NCBI Gene Symbol
MICA
NCBI GB Accession Number
MICA
Host or Source
Rabbit
Nucleotide Accession Number
NM_000247
Peptide Sequence
LRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDT
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