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PSEN1 Antibody - N-terminal region : FITC (ARP44201_P050-FITC)

Selected Variant

ARP44201_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Presenilin 1

Gene Aliases

AD3, FAD, PS1, PS-1, S182, ACNINV3

Gene ID

5663

Swiss Prot

P49768

Accession Number

NP_000012

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PSEN1

Target

Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP) . These disease-linked mutations result in increased production of the longer form o

Partner Proteins

UBC; TRAF6; TGFBR1; ERLIN2; PSMB1; PSMA5; ETFA; TDP2; PSEN2; PSEN1; APH1B; PSENEN; APH1A; NCSTN; ITSN2; PDCD4; KANK2; EPB41L3; CDC37; TUBA1B; AP1M2; UMPS; PRDX2; ST13; SCN1A; RHEB; RAD23A; RAB3A; OXCT1; NOS3; NDUFS8; HMGB1; GCDH; GAPDH; FGF13; ENSA; DTNA

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

PSEN1 is strongly supported by BioGPS gene expression data to be expressed in OVCAR3

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

53kDa

Shipping Conditions

Wet Ice

Protein Length

467

NCBI Gene Symbol

PSEN1

NCBI GB Accession Number

PSEN1

Host or Source

Rabbit

Protein Name

Presenilin-1

Nucleotide Accession Number

NM_000021

Peptide Sequence

TRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKY

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