PSEN1 Antibody - N-terminal region : Biotin (ARP44201_P050-Biotin)
Product Specifications
Gene Name
Presenilin 1
Gene Aliases
AD3, FAD, PS1, PS-1, S182, ACNINV3
Gene ID
5663
Swiss Prot
P49768
Accession Number
NP_000012
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PSEN1
Target
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP) . These disease-linked mutations result in increased production of the longer form o
Partner Proteins
UBC; TRAF6; TGFBR1; ERLIN2; PSMB1; PSMA5; ETFA; TDP2; PSEN2; PSEN1; APH1B; PSENEN; APH1A; NCSTN; ITSN2; PDCD4; KANK2; EPB41L3; CDC37; TUBA1B; AP1M2; UMPS; PRDX2; ST13; SCN1A; RHEB; RAD23A; RAB3A; OXCT1; NOS3; NDUFS8; HMGB1; GCDH; GAPDH; FGF13; ENSA; DTNA
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Sample Type
PSEN1 is strongly supported by BioGPS gene expression data to be expressed in OVCAR3
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
53kDa
Shipping Conditions
Wet Ice
Protein Length
467
NCBI Gene Symbol
PSEN1
NCBI GB Accession Number
PSEN1
Host or Source
Rabbit
Protein Name
Presenilin-1
Nucleotide Accession Number
NM_000021
Peptide Sequence
TRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKY
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