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NAT2 Antibody - middle region : Biotin (ARP44197_P050-Biotin)

Product Specifications

Gene Name

N-acetyltransferase 2 (arylamine N-acetyltransferase)

Gene Aliases

AAC2, PNAT, NAT-2

Gene ID

10

Swiss Prot

P11245

Accession Number

NP_000006

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NAT2

Target

NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2) . This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.

Partner Proteins

APP; NAA10

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

Shipping Conditions

Wet Ice

Specificity

Antibody reacts with both NAT1 and NAT2

Protein Length

290

NCBI Gene Symbol

NAT2

NCBI GB Accession Number

NAT2

Host or Source

Rabbit

Protein Name

Arylamine N-acetyltransferase 2

Nucleotide Accession Number

NM_000015

Peptide Sequence

TYRKFNYKDNTDLVEFKTLTEEEVEEVLRNIFKISLGRNLVPKPGDGSLT

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