SLCO1B1 Antibody - middle region : FITC (ARP43914_P050-FITC)
Selected Variant
ARP43914_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Solute carrier organic anion transporter family, member 1B1
Gene Aliases
LST1, HBLRR, LST-1, OATP2, OATPC, OATP-C, OATP1B1, SLC21A6
Gene ID
10599
Swiss Prot
Q9Y6L6
Accession Number
NP_006437
Host
Rabbit
Reactivity
Human, Cow, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SLCO1B1
Target
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Human: 100%; Pig: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
76kDa
Shipping Conditions
Wet Ice
Protein Length
691
NCBI Gene Symbol
SLCO1B1
NCBI GB Accession Number
SLCO1B1
Host or Source
Rabbit
Protein Name
Solute carrier organic anion transporter family member 1B1
Nucleotide Accession Number
NM_006446
Peptide Sequence
IILIYAMKKKYQEKDINASENGSVMDEANLESLNKNKHFVPSAGADSETH
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