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SLC9A3R1 Antibody - C-terminal region : FITC (ARP43877_P050-FITC)

Selected Variant

ARP43877_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1

Gene Aliases

EBP50, NHERF, NHERF1, NHERF-1, NPHLOP2

Gene ID

9368

Swiss Prot

O14745

Accession Number

NP_004243

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human SLC9A3R1

Target

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

Partner Proteins

ABCC4; UBC; MDM2; CKB; CAPN1; LDHAL6B; FTO; SMEK2; UBFD1; CNDP2; NANS; DAK; YWHAQ; GDA; NPEPPS; RPL23; YWHAZ; YWHAB; TGM2; SMS; RPS6KA3; LDHB; PDIA3; G6PD; ECHS1; CSE1L; CFTR; GNA11; PLCB1; EPHB1; PTEN; BCL10; ZNF468; gag-pol; MDH1; PALM2; PCYOX1; PPME1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

Shipping Conditions

Wet Ice

Protein Length

358

NCBI Gene Symbol

SLC9A3R1

NCBI GB Accession Number

SLC9A3R1

Host or Source

Rabbit

Protein Name

Na (+) /H (+) exchange regulatory cofactor NHE-RF1

Nucleotide Accession Number

NM_004252

Peptide Sequence

RSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQ

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