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SLC6A5 Antibody - N-terminal region : FITC (ARP43872_P050-FITC)

Selected Variant

ARP43872_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Solute carrier family 6 (neurotransmitter transporter), member 5

Gene Aliases

NET1, GLYT2, HKPX3, GLYT-2

Gene ID

9152

Swiss Prot

Q9Y345

Accession Number

NP_004202.2

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of human SLC6A5

Target

This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

Shipping Conditions

Wet Ice

Protein Length

395

NCBI Gene Symbol

SLC6A5

NCBI GB Accession Number

SLC6A5

Host or Source

Rabbit

Protein Name

Sodium- and chloride-dependent glycine transporter 2

Nucleotide Accession Number

NM_004211.3

Peptide Sequence

KNSTFCMTAYPNVTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGE

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