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SLC25A11 Antibody - N-terminal region : Biotin (ARP43849_P050-Biotin)

Product Specifications

Gene Name

Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11

Gene Aliases

OGC, PGL6, SLC20A4

Gene ID

8402

Swiss Prot

Q02978

Accession Number

NP_003553

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SLC25A11

Target

SLC25A11 catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.

Partner Proteins

RAPGEF2; UBC; SUMO2; STAU1; SUZ12; RNF2; BMI1; FBXO6; FBXO46; FBXW4; ADRB2; CLN5; CLN3; MMS19; UBL4A; MDC1; ECT2; FLOT1; HDAC5; MYC; ICT1; CEBPA; CAMKK2; BABAM1; SLC25A11; COPA; CDKN1A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SLC25A11 is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Kabe, Y., (2006) J. Biol. Chem. 281 (42), 31729-31735

Shipping Conditions

Wet Ice

Protein Length

314

NCBI Gene Symbol

SLC25A11

NCBI GB Accession Number

SLC25A11

Host or Source

Rabbit

Protein Name

Mitochondrial 2-oxoglutarate/malate carrier protein

Nucleotide Accession Number

NM_003562

Peptide Sequence

AATASAGAGGIDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQL

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