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SLC22A2 Antibody - N-terminal region : HRP (ARP43847_T100-HRP)

Selected Variant

ARP43847_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Solute carrier family 22 (organic cation transporter), member 2

Gene Aliases

45201

Gene ID

6582

Swiss Prot

O15244

Accession Number

NP_003049

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SLC22A2

Target

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A2 is one of the three similar cation transporters. SLC22A2 contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

AGO3; CST9L; LSM4; HYAL3; SUMO2; GTF2B; EXT2; ETV5; POU2AF1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 83%; Guinea Pig: 83%; Horse: 83%; Human: 100%; Mouse: 92%; Rabbit: 83%; Rat: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

62kDa

References & Citations

Pelis, R.M., Am. J. Physiol. Renal Physiol. 290 (5), F1118-F1126 (2006)

Shipping Conditions

Wet Ice

Protein Length

555

NCBI Gene Symbol

SLC22A2

NCBI GB Accession Number

SLC22A2

Host or Source

Rabbit

Protein Name

Solute carrier family 22 member 2

Nucleotide Accession Number

NM_003058

Peptide Sequence

MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR

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