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SLC18A2 Antibody - N-terminal region : Biotin (ARP43845_P050-Biotin)

Product Specifications

Gene Name

Solute carrier family 18 (vesicular monoamine), member 2

Gene Aliases

SVAT, SVMT, VAT2, VMAT2, PKDYS2

Gene ID

6571

Swiss Prot

Q05940

Accession Number

NP_003045

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SLC18A2

Target

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine.

Partner Proteins

PARK7; UBC; CSNK1A1; CSNK2A2; CSNK2A1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 86%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

References & Citations

Yamamoto, S., (2006) Neurosci. Lett. 396 (3), 187-191

Shipping Conditions

Wet Ice

Protein Length

514

NCBI Gene Symbol

SLC18A2

NCBI GB Accession Number

SLC18A2

Host or Source

Rabbit

Protein Name

Synaptic vesicular amine transporter

Nucleotide Accession Number

NM_003054

Peptide Sequence

NATRDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVQVGLLFASKAT

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