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SLC11A2 Antibody - N-terminal region : Biotin (ARP43755_P050-Biotin)

Product Specifications

Gene Name

Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

Gene Aliases

DCT1, DMT1, AHMIO1, NRAMP2

Gene ID

4891

Swiss Prot

P49281

Accession Number

NP_000608

Host

Rabbit

Reactivity

Human, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SLC11A2

Target

The SLC11A2 is a divalent metal transporter (DMT1), which carries iron, manganese, cobalt, nickel, cadmium, lead, copper, and zinc. DMT1 participates in cellular iron absorption at the luminal surface of the duodenum as well as in other areas of the body.The SLC11A2 gene encodes a divalent metal transporter (DMT1), which carries iron, manganese, cobalt, nickel, cadmium, lead, copper, and zinc. DMT1 participates in cellular iron absorption at the luminal surface of the duodenum as well as in other areas of the body (Hubert and Hentze, 2002 [PubMed 12209011]; Ludwiczek et al., 2007 [PubMed 17293870]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

NDFIP1; UBC; NEDD4; PARK2; NDFIP2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SLC11A2 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Human: 100%; Rat: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

References & Citations

Couch, R.M., (2008) Biochim. Biophys. Acta 1778 (1), 334-341

Shipping Conditions

Wet Ice

Specificity

Specific to all four isoforms of the SLC11A2 transporter.

Protein Length

561

NCBI Gene Symbol

SLC11A2

NCBI GB Accession Number

SLC11A2

Host or Source

Rabbit

Protein Name

Natural resistance-associated macrophage protein 2

Nucleotide Accession Number

NM_000617

Peptide Sequence

VLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYF

Frequently Asked Questions

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