SLC11A1 Antibody - middle region : Biotin (ARP43753_P050-Biotin)
Selected Variant
ARP43753_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Gene Aliases
LSH, NRAMP, NRAMP1
Gene ID
6556
Swiss Prot
P49279
Accession Number
NP_000569
Host
Rabbit
Reactivity
Human, Rat, Cow, Goat, Guinea Pig, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human SLC11A1
Target
SLC11A1 is a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. It controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe2+ and Mn2+, cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Goat: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Rabbit: 93%; Rat: 86%; Sheep: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
60kDa
Shipping Conditions
Wet Ice
Protein Length
550
NCBI Gene Symbol
SLC11A1
NCBI GB Accession Number
SLC11A1
Host or Source
Rabbit
Protein Name
Natural resistance-associated macrophage protein 1
Nucleotide Accession Number
NM_000578
Peptide Sequence
GYEYVVARPEQGALLRGLFLPSCPGCGHPELLQAVGIVGAIIMPHNIYLH
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